Biomedical Publications FROM PR

CONCLUSION: Results confirm high prevalence rates of current smoking and the potential impact on health among Puerto Ricans with MI diagnosis. Tailored treatments for smoking cessation for Puerto Ricans living with MI are needed.

CONCLUSION: The overall prevalence of maxillary canine impaction was high, although parallel to that reported in a Mexican population; site-level risk factors (deciduous canine presence, overlap) were identified.

CONCLUSION: The findings of this study suggest disparities in access to primary health services for people with DM between public and private insureds, and that there is no continuity of care, leading to high costs for such services.

OBJECTIVE: Cardiovascular disease (CVD) is the leading cause of death among women in Puerto Rico (PR). Cardiovascular disease risk factors (CVDRF) during pregnancy, such as obesity, type 2 diabetes (T2D), hypertension, and hypertensive disorders of pregnancy, increase risks for maternal and neonatal health. Limited data exist on CVDRF prevalence among pregnant women in PR.

CONCLUSION: Our study showed that the 6MWT can be used to evaluate SSc patients. No association was found between 6MWD and most clinical SSc symptoms in our population. Two clinical symptoms, lung crackles and palpitations, were associated with decreased 6MWD.

This case report highlights the potential of continuous ST segment monitoring (C-STM) in the emergency department (ED) for identifying transient ischemic changes in patients with acute coronary syndrome (ACS). We present a case of a 62-year-old male with type 2 diabetes and hypertension who presented with chest pain, that resolved prior to arrival. Despite an initially non-diagnostic ECG, C-STM detected transient hyperacute T waves and mild ST elevations, prompting further investigation, and...

CONCLUSIONS: These contemporary prognostic estimates are more applicable to men receiving early ADT for post-RP BCR and can help identify high-risk patients who are candidates for intensified hormonal therapy.

CONCLUSIONS: Advanced GC/GEJC patients treated with tislelizumab plus chemotherapy versus placebo plus chemotherapy in first-line had sustained and improved HRQoL. These results, along with previous efficacy and safety data, support tislelizumab plus chemotherapy as a first-line treatment option for GC/GEJC.Trial registration: The RATIONALE-305 trial is registered on ClinicalTrials.gov (ClinicalTrials.gov identifier: NCT03777657).

Testicular cancer primarily manifests as a painless mass, yet atypical presentations can hinder effective diagnosis and management. Here we present a 34-year-old male with a large, ulcerated, fungating extra-scrotal mass invading the inguinal canal. Laboratory showed markedly elevated alpha-fetoprotein, and imaging confirmed advanced disease with bilateral pulmonary metastases. The patient underwent radical orchiectomy with partial scrotectomy. Histopathology revealed a pure post-pubertal yolk...

Penetrating cardiac injuries (PCI) from gunshot wounds are among the most fatal forms of trauma, with prehospital mortality rates exceeding 90%. While the right ventricle is most commonly affected due to its anterior location, retained intracardiac projectiles are rarely encountered and pose significant management challenges. Cardiac tamponade, though potentially fatal, can sometimes provide a protective mechanism by limiting hemorrhage. The decision to surgically remove retained bullets remains...

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CONCLUSION: Anal cancer screening among MSM with HIV aged 35 years or older is cost-effective, but value-based prioritization of strategies is needed to optimize screening use.

The HPV vaccination program in Brazil, introduced in 2014 for girls and 2017 for boys, aims to reduce HPV-related diseases, including anogenital warts (AGW) and high-grade cervical intraepithelial neoplasia (CIN). This descriptive ecological study evaluated the program's impact on hospitalizations for AGW and high-grade-CIN using interrupted time series analysis of data from the Brazilian Hospital Information System from 2011 to 2019. From 2011 to 2019, there were 4,312 AGW hospitalizations...

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Detailed information of trophic interactions among consumer-resources in food webs is usually limited due to the lack of accurate identification of eaten food resources. The use of DNA-metabarcoding has been proven useful for molecular identification of the numerous taxa present in stomach contents. Here, we characterize the diet and trophic behavior of four sea urchin species inhabiting shallow waters of Puerto Rico using this molecular technique. We extracted, sequenced, and analyzed DNA from...

CONCLUSION: The preliminary findings align with the broader goal of fostering a sport culture that values both peak performance and the short- and long-term health of all participants. These results emphasise the necessity of implementing professional guidelines and comprehensive support systems designed to safeguard the long-term well-being of all athletes and underscore the urgent need for further research into the impact of TEG on sport and its community.

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This study evaluated the ovarian responses and corpus luteum (CL) functionality in Barbados Blackbelly × White Virgin Island crossbred hair sheep subjected to two estrous synchronization protocols in a tropical grazing environment. A total of 40 non-lactating ewes, between 2 and 4 years of age, were randomly assigned to one of two treatment groups. The CIDR + PG group (n = 20) received a 7-day intravaginal CIDR device containing 0.3 g of progesterone, followed by an intramuscular injection of 10...

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CONCLUSIONS: The quantitative analysis of these biomarkers, along with the subsequent sensitive and specific clinical classification, highlights their potential application in SIL early detection and CC prevention, particularly in LMICs.