Ultrasound assessment of hepatomegaly and metabolically-associated fatty liver disease among a sample of children: a pilot project

1 month ago
Bárbara L Riestra-Candelaria
INTRODUCTION: Obesity in children is a global health crisis, with 46% of children in Puerto Rico classified as overweight or obese based on Body Mass Index. This condition is linked to serious comorbidities, including early-onset type 2 diabetes, hypertension, and Metabolic-Associated Fatty Liver Disease (MAFLD), the most common liver disease in U.S. children. This study examines the relationship between body weight, liver size, and texture in children from Puerto Rico.

Patterns and Outcomes of Craniomaxillofacial Trauma in Puerto Rico: Insights From a Five-Year Retrospective Study

1 month ago
Raúl Y Ramos-Sánchez
Background Craniomaxillofacial (CMF) trauma is a significant problem in the United States, with estimated costs of nearly one billion dollars annually. Facial fractures occur based on factors such as facial structure, the direction and intensity of the impact, and the mechanism of injury. The most frequent facial fractures include the nose, orbits, zygomatic complex, mandible, maxilla, and frontal bone. Additionally, demographic, social, cultural, and environmental factors can contribute to...

Postoperative Pain Management With Ketorolac, Acetaminophen, and Gabapentin in Femoral Shaft Fractures: A Prospective Cohort Study

1 month ago
Hans Hess Arcelay
CONCLUSION: The study concludes that the coadministration of ketorolac, acetaminophen, and gabapentin is an effective opioid-sparing alternative for postoperative pain in isolated femur shaft fractures. Future research could benefit from a more diverse patient population in orthopaedic trauma to further validate our results and explore long-term outcomes.

Environmental heterogeneity across an urban gradient influences detritus and nutrients within artificial containers and their associated vector Aedes sp. larvae in San Juan, Puerto Rico

1 month 1 week ago
Limarie J Reyes-Torres
Detrital inputs from the surrounding terrestrial environment provide essential nutrients that sustain mosquito populations in aquatic containers. The larvae of Aedes aegypti (L.), an anthropophilic invasive vector species, often develop in artificial habitats in urban areas but little is known about how that environment shapes their life history or phenotypic traits. We hypothesized that container detritus, nutrients, and larval interspecific competition with the endemic mosquito, Aedes...

The innexin 7 gap junction protein contributes to synchronized activity in the <em>Drosophila</em> antennal lobe and regulates olfactory function

1 month 1 week ago
Nicolás Fuenzalida-Uribe
In the mammalian olfactory bulb (OB), gap junctions coordinate synchronous activity among mitral and tufted cells to process olfactory information. In insects, gap junctions are also present in the antennal lobe (AL), a structure homologous to the mammalian OB. The invertebrate gap junction protein ShakB contributes to electrical synapses between AL projection neurons (PNs) in Drosophila. Other gap junction proteins, including innexin 7 (Inx7), are also expressed in the Drosophila AL, but little...

Age-related neutrophil activation in Hermansky-Pudlak Syndrome Type-1

1 month 1 week ago
Lourdes Marinna Caro-Rivera
Hermansky-Pudlak Syndrome (HPS) type 1 (HPS-1) is an autosomal recessive disorder characterized by oculocutaneous albinism, platelet dysfunction, and pulmonary fibrosis (HPS-PF), the leading cause of mortality in these patients. HPS-PF manifests earlier than idiopathic pulmonary fibrosis, typically between 30 and 40 years of age. The etiology and drivers of HPS-PF progression remain poorly understood, and no FDA-approved therapies exist. Neutrophil extracellular traps (NETs) and...

Henkel: Data Engineer R&D (d/f/m)

1 month 1 week ago
Competitive: Henkel: About this Position Join Our Digital R&D Team at Henkel and work in a cross-functional and agile R&D Digitalization Team that enables a global R&D... Düsseldorf, North Rhine Westphalia, Germany

Henkel: Application Engineering Manager

1 month 1 week ago
Competitive: Henkel: About this Position Application Engineer Manager is responsible for leading the APC (Consumer Goods) Indonesia Application Engineering team and pro... Pasuruan, Jawa, Indonesia

Switching Therapy to the Second Brand of Generic Atorvastatin: A 6-Month Retrospective Cohort, Real-World Study

1 month 1 week ago
Panisa Manasirisuk
CONCLUSIONS: The second generic atorvastatin (Lipostat^(®)) resulted in comparable outcomes on LDL compared with the original (Xarator^(®)), but significantly lower LDL levels than another generic atorvastatin (Atorvastatin Sandoz^(®)) 6 months after switching therapy. However, renal function should be closely monitored.

Juntas Contra el Virus del Papiloma Humano: protocol for a pilot randomized controlled trial of an HPV self-sampling intervention for underscreened Latinas

1 month 1 week ago
Carolyn Y Fang
BACKGROUND: Rates of cervical cancer incidence and mortality are persistently higher among Latina women in the continental United States (US) and women in Puerto Rico (a US territory) compared with non-Hispanic White (NHW) women. Multiple factors contribute to low participation in cancer screening, including structural barriers (e.g., low access to healthcare services, racism/discrimination, lack of culturally and linguistically adequate information), cultural concerns, and low perceived risk...

Urbanisation Affects Millipede Gut Microbiota Communities by Impeding Host Gene Flow

1 month 1 week ago
Hongyi Liu
Urbanisation leads to the alteration of the living environment of soil fauna and isolates them, significantly influencing the evolutionary processes of soil fauna. Faunal gut microbiota serves to bridge hosts with changing environments; thus, they are viable indicators of host adaptation. For this study, we investigated how urbanisation affects the gut microbiota and population genetics of Spirobolus bungii. The results revealed that urbanisation did not affect the genetic diversity of S. bungii...