PEBL, a component-based Chinese medicine, reduces virus-induced acute lung injury by targeting FXR to decrease ACE2 levels

1 month 2 weeks ago
Liling Yang
CONCLUSIONS: This study provides the first evidence that PEBL offers protective effects against ALI induced by acute respiratory viruses. PEBL prevents FXR from binding to ACE2 by inhibiting FXR transcription, which reduces macrophage infiltration, cytokine storm formation, and inflammatory injury, thereby ameliorating viral ALI. These findings underscore the potential of PEBL as a candidate for further exploration in the treatment of viral ALI.

Science and Technology Centers: Integrative Partnerships (STC)

1 month 2 weeks ago
Full Proposal Deadline Date: June 2, 2025

Program Guidelines: NSF 24-594

The Science and Technology Centers (STC): Integrative Partnerships program supports exceptionally innovative, complex research and education projects that require large-scale, long-term awards. STCs focus on creating new scientific paradigms, establishing entirely new scientific disciplines, and developing transformative technologies which have the potential for broad scientific or societal impact. STCs conduct world-class research through partnerships among institutions of higher ...
More at https://beta.nsf.gov/programid/5541


This is an NSF Upcoming Due Dates item.

EPSCoR Graduate Fellowship Program (EGFP)

1 month 2 weeks ago
Full Proposal Deadline Date: June 2, 2025

Program Guidelines: NSF 24-588

The NSF EPSCoR Graduate Fellowship Program (EGFP) provides an opportunity for applicants who received the distinction of GRFP Honorable Mention no more than three years before the proposal due date to be named NSF EPSCoR Graduate Fellows and obtain financial support for their graduate education at an institution in an EPSCoR jurisdiction. EGFP aims to enhance the capacity and competitiveness of EPSCoR jurisdictions by providing funding to graduate degree-awarding institutions to support NSF ...
More at https://beta.nsf.gov/programid/506310


This is an NSF Upcoming Due Dates item.

Cyber-Physical Systems (CPS)

1 month 2 weeks ago
Full Proposal Window: June 2, 2025
SMALL and MEDIUM Proposals. Accepted anytime during the year-long annual submission window.

Program Guidelines: NSF 24-581

Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computation and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will expand the horizons of these critical systems. CPS technologies are transforming the way people interact with engineered systems, just as the Internet has transformed the way people interact with information. New, smart ...
More at https://beta.nsf.gov/programid/503286


This is an NSF Upcoming Due Dates item.

Antarctic Research Requiring U.S. Antarctic Program (USAP) Support for Fieldwork

1 month 2 weeks ago
Full Proposal Deadline Date: June 2, 2025
Prior to submission of full proposals, investigators are required to submit a Concept Outline, which is due January 31, 2025 and January 15 Annually Thereafter.

Program Guidelines: NSF 25-525

Through this solicitation, the Antarctic Sciences Section (ANT) of the Office of Polar Programs (OPP) funds cutting-edge research that requires logistical support from the U.S. Antarctic Program (USAP) and:

  • Improves understanding of interactions among the Antarctic region and global systems.
  • Improves understanding of the dynamic linkages among processes operating in the Antarctic and Southern Ocean and linkages to global Earth systems, which helps inform ...
    More at https://beta.nsf.gov/programid/506093


    This is an NSF Upcoming Due Dates item.

Antarctic Research Not Requiring U.S. Antarctic Program (USAP) Field Support

1 month 2 weeks ago
Full Proposal Target Date: June 2, 2025

Program Guidelines: NSF 25-526

Through this solicitation, the Antarctic Sciences Section (ANT) of the Office of Polar Programs (OPP) funds cutting-edge research that:

  • Improves understanding of interactions among the Antarctic region and global systems.
  • Improves understanding of the dynamic linkages among processes operating in the Antarctic and Southern Ocean and linkages to global Earth systems, which helps inform decision making regarding environmental change.
  • Advances fundamental ...
    More at https://beta.nsf.gov/programid/506099


    This is an NSF Upcoming Due Dates item.

Henkel: Technology Transfer Head

1 month 2 weeks ago
Competitive: Henkel: Acerca de esta posición El/la Technology Transfer Head será responsable de liderar y garantizar la transferencia tecnológica de fórmulas y material... Bogotá, Distrito Capital De Bogotá, Colombia

General Consensus on Implementing an Episode-Based Payment Model: Results From the American College of Radiation Oncology (ACRO) Payment Reform Survey

1 month 2 weeks ago
Joseph A Wilding
Introduction Medicare payments for radiation oncology (RO) services adhere to a fee-for-service model. However, a growing number of stakeholders, including both payers and physicians, are increasingly supportive of transitioning to an episode-based payment (EBP) model. Multiple novel models have been proposed, including the Centers for Medicare and Medicaid Services/Center for Medicare & Medicaid Innovation Radiation Oncology Model and the American Society for Radiation Oncology Radiation...