Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

6 days 10 hours ago
Funding Opportunity PA-25-422 from the NIH Guide for Grants and Contracts. The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral (Parent F31) award is to enable promising predoctoral students will obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research projects in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training must reflect the candidates dissertation research project and is expected to clearly enhance the individuals potential to develop into a productive, independent research scientist. This Notice of Funding Opportunity (NOFO) does not allow candidates to propose to lead an independent clinical trial but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

6 days 10 hours ago
Funding Opportunity PA-25-426 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) will support students at institutions with NIH-funded institutional predoctoral dual-degree training programs. The purpose of the Kirschstein-NRSA, dual-doctoral degree, predoctoral fellowship (F30) is to enhance the integrated research and clinical training of promising predoctoral students, who are matriculated in a combined MD/PhD or other dual-doctoral degree training program (e.g. DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD), and who intend careers as physician/clinician-scientists. Candidates must propose an integrated research and clinical training plan and a dissertation research project in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The fellowship experience is expected to clearly enhance the individual's potential to develop into a productive, independent physician/clinician-scientist. This Notice of Funding Opportunity (NOFO) is designed specifically for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial, but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

Treatment of polyarticular juvenile idiopathic arthritis in Latin America: recommendations from the Pan-American League of Associations for Rheumatology

6 days 15 hours ago
Raúl Gutiérrez-Suárez
To develop evidence-based treatment guidelines for non-systemic polyarticular-juvenile idiopathic arthritis (poly-JIA) in Latin America, endorsed by the Pan-American League of Associations for Rheumatology (PANLAR), a panel of paediatric rheumatologists from Latin America formulated clinically relevant questions regarding polyarthritis treatment, using the Population, Intervention, Comparator, and Outcome (PICO) format. Following the Grading of Recommendations Assessment, Development, and...

Magnetic Moment Descriptor-Guided Multifunctional Co Single-Atom Catalysts Enable Wide-Temperature Uninterrupted Seawater Splitting

6 days 15 hours ago
Canhui Zhang
Developing chloride ion-resistant trifunctional catalysts is imperative and of great significance for application in renewable energy-driven seawater splitting systems (S-WSS). However, there is currently a lack of unified descriptors for the rational design of catalysts that possess both high corrosion resistance and excellent catalytic activity. Herein, the magnetic moment is proposed as the descriptor through second-coordination-shell anion engineering of CoN₄ moieties (named as CoN(4)-X, X =...

Cancer Incidence and Trends in US Adults With HIV

6 days 15 hours ago
Cameron B Haas
CONCLUSIONS AND RELEVANCE: In this cohort study, significant declines in the incidence and relative risk for cancers among people with HIV demonstrate continued progress in HIV treatment and cancer prevention. These estimates may provide insight into the priorities for prevention and early detection of cancer as the population of people with HIV enters ages with greater risk for cancer.

Sustained Effectiveness, Tolerability, and Safety of Long-Term Prophylaxis with Lanadelumab in Hereditary Angioedema: The Prospective, Phase 4, Noninterventional EMPOWER Real-World Study

6 days 15 hours ago
Jonathan A Bernstein
CONCLUSION: Real-world data from EMPOWER showed marked HAE attack rate reduction up to 36 months after initiating lanadelumab in patients newly treated with lanadelumab and maintenance of low attack rates in patients established on lanadelumab. No new safety signals were identified.

Wind acclimation in a subtropical forest: trees on wind-exposed slopes are shorter with smaller crowns

6 days 15 hours ago
Roi Ankori-Karlinsky
Tree architecture is an important component of forest community dynamics - taller trees with larger crowns often outcompete their neighbors, but they are generally at higher risk of wind-induced damage. Yet, we know little about wind impacts on tree architecture in natural forest settings, especially in complex tropical forests. Here, we use airborne light detection and ranging (LiDAR) and 30 yr of forest inventory data in Puerto Rico to ask whether and how chronic winds alter tree architecture....

Wind acclimation in a subtropical forest: trees on wind-exposed slopes are shorter with smaller crowns

6 days 15 hours ago
Roi Ankori-Karlinsky
Tree architecture is an important component of forest community dynamics - taller trees with larger crowns often outcompete their neighbors, but they are generally at higher risk of wind-induced damage. Yet, we know little about wind impacts on tree architecture in natural forest settings, especially in complex tropical forests. Here, we use airborne light detection and ranging (LiDAR) and 30 yr of forest inventory data in Puerto Rico to ask whether and how chronic winds alter tree architecture....